Solubilization of lycopene in jojoba oil microemulsion.


Nissim Garti, Marina Shevachman, and Arnon. Shani. 2004. “Solubilization of lycopene in jojoba oil microemulsion.” Journal of the American Oil Chemists' Society, 81, 9, Pp. 873–877.


The unique properties of jojoba oil make it an essential raw material in the manuf. of cosmetics. New, totally dilutable U-type microemulsions of water, jojoba oil, alcs., and the nonionic surfactant polyoxyethylene-10EO-oleyl alc. (Brij 96V) were formulated recently. Here, these microemulsions are shown to be capable of solubilizing lycopene, a nutraceutical insol. in water and/or oil, much more effectively than the solvent (or a solvent and surfactant blend) can dissolve them. In water-in-oil (W/O) and oil-in-water (O/W) microemulsions with 10 and 90 wt% water, resp., the normalized maximal solubilization efficiency $\alpha$ is ca. 20-fold larger than its soly. The solubilization capacity of the system is mainly surfactant-concn. dependent. The lycopene resides at the interfaces of the W/O and O/W microemulsions and engenders significant structural changes in the organization of the microemulsion droplets. In the absence of lycopene, the droplets are spherical; when lycopene is added, compaction of the droplets and formation of threadlike droplets are obsd. On further addn. of lycopene, the bridging effect wanes and the droplets revert to a spherical shape. The enhanced solubilization demonstrated for lycopene opens up new options for formulators interested in making liq. and transparent products for cosmetic or pharmaceutical uses. [on SciFinder(R)]
Last updated on 06/28/2020