Abstract:

Cholesterol was crystd. under various conditions from a range of solvents, and the effects of the solvents on the crystal structure were studied. The phase transitions and the latent heat, $Δ$Hp, were measured and were found to vary from 0.18 kcal mole-1 (for CCl4) to 1.1 kcal mole-1 (for acetonitrile). It seems possible that the polymorphic transitions of cholesterol at 37° may be divided into several subtransitions, each one corresponding to a slight configurational change that can be attributed to a possible flip-over of the aliph. chain of the cholesterol. [on SciFinder(R)]