Abstract:

In our recent studies we have found a unique mixt. of water, special food-grade oil, mixt. of food-grade surfactants, cosolvent (polyol) and coemulsifiers that can self-assemble to form new nanosized modified microemulsions of U-type, totally dilutable with aq. phase. The "conc." is capable of solubilizing nutraceuticals that are poorly sol. in water or oil phase at ca 15-20 folds over their soly. capacity. Nutraceuticals such as lycopene, lutein, CoQ10, phytosterols, etc. have been solubilized. We have used advanced techniques such as SAXS, SANS, SD-NMR, QELS to evaluate the microstructures in the absence and in the presence of the guest mols. The presentation will bring data on the solubilization of the nutraceuticals, their chem. protection against oxidn., and their improved bioavailability. Effects of guest mols. and microemulsions ingredients on the microstructure transitions and reactivity will be discussed. [on SciFinder(R)]