Cubosomes as delivery vehicles.

Citation:

Nissim Garti, Amar-Yuli, Idit , Libster, Dima , and Aserin, Abraham. . 2009. “Cubosomes As Delivery Vehicles.”. In Highlights Colloid Sci., Pp. 279–290. New-York: Wiley-VCH Verlag GmbH & Co. KGaA. doi:10.1002/9783527623884.ch15.

Abstract:

A review on cubosomes, nanosoft particles that are formed when the liq. cryst. cubic phases are dispersed in aq. phase contg. a stabilizer (usually amphiphilic polymer), and their potential use as drug delivery vehicles. In the dispersed soft matter particles, the nanostructure of the original cubic inner structure remains intact despite the dispersion process. The three-dimensional symmetry of the cubic phases, combined with their large interfacial area and balanced content of hydrophobic and hydrophiic domains, make them very promising universal drug carriers, with numerous advantages over most other systems used at present. These exceptional phys. and chem. properties stimulated the study of the liq. crystal dispersions. Thus, one can take advantage of the complex phases for controlled delivery, while simultaneously having the benefit of the low viscosity of a system of soft nanoparticles dispersed in a continuous aq. phase. [on SciFinder(R)]
Last updated on 05/27/2020